THEPAX® is a food supplement based on selected, inactivated and stabilized cells of Saccharomyces Cerevisiae, good at modulating intestinal and rumen flora.

Thanks to the application of the most advanced biotechnological breakthroughs, the yeast cell remains intact and preserves a high content of prebiotic substances useful in stimulating metabolic processes.


And you optimize the administration of feed.





Thepax® contributes to increase the number of digestive microflora in order to help the animals to better utilize the feed. Its action:

• Releases of nutrients to microflora
• Increases number of digestive bacteria population, thus keeping rumen pH fluctuations
• Improves FRC
• Increases animal performance
• Decreases production unit cost


Thepax® help large intestine microflora to limit the growth of pathogenic bacteria, by direct and indirect effects:

• Reduces incidence of abnormal fermentation with reduction in toxin production
• Allows a rapid recovery of digestive micro flora following antibiotic treatments
• Improves resistance to stress
• Improves performances, by increasing feed intake and FCR
• Improves the animal overall health and conditions

Since ever, combinations of yeasts, microbial products, and enzymes are said to improve cellulose digestion, feed intake, and animal performance. Live yeast and other species of bacterial cells have been added to feed on the assumption that their introduction into the rumen would add to the rumen fermentation.


But yeasts, Lactobacillus, and other microbes do not survive in the rumen, although a small population can probably be maintained by continuous feeding.


In case of dried yeast it has to be considered that nutrients are seriously spoiled because of the breaking of the cell wall.

To be effective:


  • It should not have any activity that delays the release of these substances in rumen/gut
  • It has to keep its content intact until it reaches the rumen/gut
  • The cell wall must be degraded in rumen/gut
  • It must have a high number of cells per g of product

Yeasts are eukaryotic, single-celled microorganisms that carry out all the functions of a living cell:


  • It consumes nutrients
  • It produces catabolites
  • It reproduces itself
  • It delays releasing nutrients
  • It competes with other microorganisms

Technological processes for the production of dried yeast aim to eliminate water, and often damage cell walls and yeast cells.


The microscopic vision of a dried yeast shows how the cell walls have been destroyed and it’s easy to understand that the nutritional components have been used up.


Dried yeast is only a source of proteins.

THEPAX® makes the difference

THEPAX® is a concentrate of inactivated and stabilized cells of Saccharomyces cerevisiae.

The number of inactivated and intact cells is of 5,05 x 109 per gram of product and it guarantees a hight content of natural prebiotic substances, useful for the growth of ruminal and intestinal microflora.

The inactivation of yeast allows to obtain:

Increased availability of fresh nutrients

Immediate release of active substances contained in cells

Reduction of uncontrolled fermentative activities

Resistance to pressure and high temperatures and, therefore, greater flexibility in processing and greater stability in storage

The benefits of the yeast natural insctivated

Suitable for monogastrics and ruminants

Fresh nutrients

Resistance to dramatic pH changes (pH2)

Suitable for pelleting and extrusion processes

Temperature resistance (20 minutes at 120°C)

Long shelf-life

Antibiotic resistance

More bioactivity for the microflora

Rich in content
The inactivation process takes place in the initial phase of the budding process: the cells of Saccharomyces cerevisiae are fixed at the stage of pre-mitosis and preserve intact the nutrients inside the cell:

Vitamins and trace elements



Malic Acid


Glutamin Acid



The cells of Thepax® also keep intact the cell wall which, rich in MOS and glucans, acts as a stimulus to the body’s immune response.

Quality assured

Thepax® bioactivity is constantly assayed in our laboratory.


It is expressed as the ratio between the bacterial growth of Lactobacillus acidophilus ATCC C-5M 20.9 in cultures with and without Thepax®, after few hours of incubation.


The assay is routinely used for every batch of Thepax® products, which must achieve a minimum bioactivity coefficient of 2.5 to be validated.


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Last update: November 2020